phosphatidylinositol 4,5-bisphosphate

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phos·pha·ti·dyl·in·o·si·tol 4,5-·bis·phos·phate (PIP2, PtdIns(4,5)P2),

phosphatidylinositol with two additional sites of phosphorylation; an important constituent of cell membrane phospholipids as well as a precursor of the second messengers, diacylglycerol and inositol 1,4,5-trisphosphate.
References in periodicals archive ?
ADP-ribosylation factor 6 regulates mammalian myoblast fusion through phospholipase D1 and phosphatidylinositol 4,5-bisphosphate signaling pathways.
Cholifa-Caspi V, Yona E, Discovitch M (1998) Kinetic analyses in mixed micelles of partially purified rat brain phospholipase D activity and its inactivation by phosphatidylinositol 4,5-bisphosphate.

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