(redirected from Phosphatidyl inositol)

phos·pha·ti·dyl·in·o·si·tol (PtdIns),

A phosphatidic acid combined with inositol found in biomembranes and a precursor to certain cellular signals. Sometimes referred to as inositide.
Synonym(s): phosphoinositide
References in periodicals archive ?
Commercial lecithin is a mixture of several natural phospholipids (phosphatidyl choline, phosphatidyl inositol, phosphatidyl ethanolamine, and phosphatidic acid) in oil.
This leads to employment of insulin receptor substrate (IRS) proteins, followed by activation of phosphatidyl inositol 3 kinase (PI3K) and subsequent translocation of glucose transporter-4 (Glut-4) and glucose uptake by the cells (Wilcox 2005).
Thus, depression is accompanied by increased levels of plasma IgG antibodies against oxidized LDL; and increased IgM-mediated immune responses against membrane fatty acids, like phosphatidyl inositol (Pi); oleic, palmitic, and myristic acid; and NO modified amino-acids, e.
Apigenin and quercetin are inhibitors of the phosphatidyl inositol kinase (PI3K) pathway (Jeong 1999).
A major pathway for metabolic effects of insulin and other growth factors is phosphatidyl inositol 3-kinase (PI3K).
Its major function relies on its phosphatase activity and subsequent antagonism of the phosphatidyl inositol 3 kinase (PI3K)/AKT pathway.
Inositol Phospholipid Metabolism and Phosphatidyl Inositol Kinases
Data on certain early key events in the T cell activation pathways, obtained from iron-deficient murine splenic T lymphocytes, show reductions in hydrolysis of cell membrane phosphatidyl inositol 4, 5 bisphosphate, protein kinase C activation, and interleukin-2 secretion.
Calpain, a thiol protease, is responsible for the cleavage of several adhesion structural proteins (talin and integrin [Alpha]II[Beta]3) (9,10) and signaling enzymes [focal adhesion kinase (FAK); phosphatidyl inositol 3-kinase (PIK)] (11,12) in spreading and aggregating platelets.