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phorbol
(redirected from Phorbol esters)

    Also found in: Wikipedia 0.01 sec.
phorbol /phor·bol/ (for´bol) a polycyclic alcohol occurring in croton oil; it is the parent compound of the phorbol esters.
phorbol ester  any of several esters of phorbol that are potent cocarcinogens, activating a cellular protein kinase; used in research to enhance the induction of mutagenesis or tumors by carcinogens.
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In contrast, topical application of phorbol esters (like PMA) induce a long-lasting inflammatory response associated with a transient increase in prostanoid production and marked cellular influx.
Protective effects of a standard extract of Mangifera indica L. ... by Garrido, G.; Gonzalez, D.; Lemus, Y.; Delporte, C.; Delgado, R. / Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
v-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: effects of phorbol esters and retinoic acid.
Biokinetics and subchronic toxic effects of oral arsenite, arsenate, ... by Germolec, Dori R. / Environmental Health Perspectives
Direct activation of PKC by phorbol esters (PMA) or a PMA analog, phorbol 12, 13 dibutyrate, desensitizes the receptor.
Biomedicine & biotechnology senior section by Witkowski, Colette M. / Transactions of the Missouri Academy of Science
 
 
 
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