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phorbol
(redirected from Phorbol ester)

    Also found in: Wikipedia 0.01 sec.
phorbol /phor·bol/ (for´bol) a polycyclic alcohol occurring in croton oil; it is the parent compound of the phorbol esters.
phorbol ester  any of several esters of phorbol that are potent cocarcinogens, activating a cellular protein kinase; used in research to enhance the induction of mutagenesis or tumors by carcinogens.
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Substances such as phorbol ester and okadaic acid, which are promoters of skin cancer, are also strong inducers of the NF[kappa]B response in keratinocytes (Budunova et al.
Cyclooxygenase-2 induction by arsenite through the ... by Ouyang, Weiming; Zhang, Dongyun; Ma, Qian; Li, Jingxia; Huang, Chuanshu / Environmental Health Perspectives
Reciprocal interactions between protein kinase C and components of the NADPH oxidase complex may regulate superoxide production by neutrophils stimulated with a phorbol ester.
In vitro activation of hemocytes from the American lobster, Homarus ... by Beaven, Amy E. / Journal of Shellfish Research
Direct activation of PKC by phorbol esters (PMA) or a PMA analog, phorbol 12, 13 dibutyrate, desensitizes the receptor.
Biomedicine & biotechnology senior section by Witkowski, Colette M. / Transactions of the Missouri Academy of Science
 
 
 
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