phenelzine sulfate


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phenelzine sulfate

[fē′nəlzēn]
a monoamine oxidase inhibitor.
indications It is prescribed in the treatment of depression, especially atypical endogenous depression and depression associated with adverse life events.
contraindications Liver dysfunction, congestive heart failure, pheochromocytoma, concomitant use of sympathomimetic drugs or foods high in tryptophan or tyramine, or known hypersensitivity to this drug prohibits its use.
adverse effects Among the most serious adverse effects are orthostatic hypotension, vertigo, constipation, blurred vision, headache, overactivity, and dryness of the mouth. Monoamine oxidase inhibitors produce many adverse drug interactions.

phenelzine sulfate (fen´əlzēn´ sul´fāt),

brand name: Nardil;
drug class: antidepressant, monoamine antioxidase inhibitor;
action: increases concentrations of endogenuous epinephrine, norepinephrine, serotonin, dopamine in storage sites in central nervous system;
use: depression when uncontrolled by other means.