periodic acid-Schiff stain


Also found in: Encyclopedia, Wikipedia.

per·i·od·ic ac·id-·Schiff stain (PAS),

(shif),
a tissue-staining procedure in which 1,2-glycol groupings are first oxidized with periodic acid to aldehydes that then react with the sulfite leucofuchsin reagent of Schiff and turn red-violet; strong staining occurs with polysaccharides, such as glycogen, and mucopolysaccharides of epithelial mucins, basement membranes, and connective tissue.
Synonym(s): PAS stain

Schiff,

Hugo, German chemist in Florence, 1834-1915.
Kasten fluorescent Schiff reagents - see under Kasten
ninhydrin-Schiff stain for proteins
periodic acid-Schiff stain - a tissue-staining procedure. Synonym(s): PAS stain
Schiff base - condensation products of aldehydes and ketones with primary amine. Synonym(s): aldimine
Schiff reagent - used for aldehydes and in histochemistry to detect polysaccharides, DNA, and proteins.

per·i·od·ic ac·id-Schiff stain

(PAS) (pērē-odik asid shif stān)
A clinical tissue-staining procedure.
Mentioned in ?
References in periodicals archive ?
Psammomatous calcification (A) and periodic acid-Schiff stain positive hyaline bodies (B) were seen in the tumour stroma (arrowed) (x100).
A rare cause of childhood renal cysts: Xp11.2 translocation renal cell carcinoma
The periodic acid-Schiff stain did not demonstrate cytoplasmic staining of the cells in the epidermis.
Treatment of extramammary Paget disease with topical imiquimod cream: case report and literature review
Tinea faciei can induce a psoriasiform as well as a spongiotic reaction pattern, and therefore, a periodic acid-Schiff stain is appropriate in this setting as well.
Biopsies of Facial Dermatoses Made Simple
There were numerous yeastlike organisms seen with this stain but not with the periodic acid-Schiff stain.
Small-intestine Pneumocystis jiroveci pseudotumor as an acquired immunodeficiency syndrome--presenting illness: report of a case and review of the literature
A periodic acid-Schiff stain indicated absence of glycogen deposits.
Resolution of giant cell myocarditis after extended ventricular assistance
Periodic acid-Schiff stain failed to demonstrate glycogen particles in the cytoplasm of the cells.
Epithelioid leiomyosarcoma of the external deep soft tissue
3,4) Mucicarmine and periodic acid-Schiff stain the characteristic thick mucopolysaccharide capsule.
Systemic symptoms in a human immunodeficiency virus type 1--positive 30-year-old man. (Pathologic Quiz Case)
Periodic acid-Schiff stain demonstrated the presence of positive granules in the cytoplasm of nucleated red blood cells and some blasts (Figure 2).
Pathologic quiz case: nonimmune hydrops in a newborn. (Residents' Pages)
Mucicarmine stain was negative and periodic acid-Schiff stain was positive and seen decorating the cell membrane.
Glassy Cell Carcinoma of the Endometrium: A Case Report and Review of the Literature
A periodic acid-Schiff stain was focally positive, and the positivity was abolished by diastase digestion.
Primitive Neuroectodermal Tumor of the Lung
Acid-fast bacilli and periodic acid-Schiff stains were negative.
Nodules on nose and tattoos
Periodic acid-Schiff stains demonstrated occasional yeast cells thought to be Pityrosporum.
Terra firma-forme dermatosis

Medical browser ?
Full browser ?