periodic acid-Schiff stain
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per·i·od·ic ac·id-·Schiff stain (PAS),
(shif),a tissue-staining procedure in which 1,2-glycol groupings are first oxidized with periodic acid to aldehydes that then react with the sulfite leucofuchsin reagent of Schiff and turn red-violet; strong staining occurs with polysaccharides, such as glycogen, and mucopolysaccharides of epithelial mucins, basement membranes, and connective tissue.
Synonym(s): PAS stain
Schiff,
Hugo, German chemist in Florence, 1834-1915.Kasten fluorescent Schiff reagents - see under Kasten
ninhydrin-Schiff stain for proteins
periodic acid-Schiff stain - a tissue-staining procedure. Synonym(s): PAS stain
Schiff base - condensation products of aldehydes and ketones with primary amine. Synonym(s): aldimine
Schiff reagent - used for aldehydes and in histochemistry to detect polysaccharides, DNA, and proteins.
per·i·od·ic ac·id-Schiff stain
(PAS) (pērē-odik asid shif stān)A clinical tissue-staining procedure.