periodic acid-Schiff stain

per·i·od·ic ac·id-·Schiff stain (PAS),

(shif),

a tissue-staining procedure in which 1,2-glycol groupings are first oxidized with periodic acid to aldehydes that then react with the sulfite leucofuchsin reagent of Schiff and turn red-violet; strong staining occurs with polysaccharides, such as glycogen, and mucopolysaccharides of epithelial mucins, basement membranes, and connective tissue.

Synonym(s): PAS stain

Schiff,

Hugo, German chemist in Florence, 1834-1915.

Kasten fluorescent Schiff reagents - see under Kasten

ninhydrin-Schiff stain for proteins

periodic acid-Schiff stain - a tissue-staining procedure. Synonym(s): PAS stain

Schiff base - condensation products of aldehydes and ketones with primary amine. Synonym(s): aldimine

Schiff reagent - used for aldehydes and in histochemistry to detect polysaccharides, DNA, and proteins.

per·i·od·ic ac·id-Schiff stain

(PAS) (pērē-odik asid shif stān)

A clinical tissue-staining procedure.

References in periodicals archive ?

The results of the periodic acid-Schiff stain (Figure 1, A through C) for tissue glycogen showed basement-membrane thickening in connective tissues and basal laminae in FBMN, but in FSGS, it revealed a well-delineated, rounded glomerulosclerosis that adhered to the Bowman capsule, with the appearance of a small fibrosis.

Attributes of antiangiogenic factor plasminogen kringle 5 in glomerulonephritis

Psammomatous calcification (A) and periodic acid-Schiff stain positive hyaline bodies (B) were seen in the tumour stroma (arrowed) (x100).

A rare cause of childhood renal cysts: Xp11.2 translocation renal cell carcinoma

The periodic acid-Schiff stain did not demonstrate cytoplasmic staining of the cells in the epidermis.

Treatment of extramammary Paget disease with topical imiquimod cream: case report and literature review

And if you do a biopsy, always do a periodic acid-Schiff stain on the specimen," Dr.

Onycholysis dx requires medical detective work

Acidfast bacteria and periodic acid-Schiff stain results were negative.

Small-intestine Pneumocystis jiroveci pseudotumor as an acquired immunodeficiency syndrome--presenting illness: report of a case and review of the literature

Fungal elements were visible on periodic acid-Schiff stain.

Blastoschizomyces capitatus pneumonia in an immunocompetent male

Characteristically, the tumor cells were densely pigmented with melanin, which was positive for Fontana-Masson (Figure 3) and periodic acid-Schiff stains but negative for Berlin-blue stain.

Pigmented perivascular epithelioid cell tumor of the kidney

Because hyaluronidase-sensitive material may be encountered in mesotheliomas, digested periodic acid-Schiff stains have been recommended for neutral ("epithelial") mucins because this finding is almost entirely restricted to adenocarcinoma.

Guidelines for pathologic diagnosis of malignant mesothelioma: a consensus statement from the International Mesothelioma Interest Group

Paraffin-embedded tissues from endobronchial biopsies, TBB, and postmortem lung samples were studied histologically using hematoxylin-eosin, Giemsa, and periodic acid-Schiff stains.

Coexistence of acute cellular rejection and lymphoproliferative disorder in a lung transplant patient

These organisms were gram-negative and highlighted by Warthin-Starry (Figure 4) and periodic acid-Schiff stains.

Supraglottic Granulomas in a Young Central American Man

No hyaline globules were seen in the endothelial cells on hematoxylin-eosin or periodic acid-Schiff stains.

Low-grade clear cell renal cell carcinoma mimicking hemangioma of the kidney: a series of 4 cases