pepsin (redirected from Pepsin B)

pepsin /pep·sin/ (pep´sin) the proteolytic enzyme of gastric juice which catalyzes the hydrolysis of native or denatured proteins to form a mixture of polypeptides; it is formed from pepsinogen in the presence of acid or, autocatalytically, in the presence of pepsin.

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pep·sin or pep·sine (ppsn)

n.

1. Any of various digestive enzymes found in gastric juice that catalyze the hydrolysis of proteins to peptides.

2. A substance containing pepsin, obtained from the stomachs of hogs and calves and used as a digestive aid.

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pepsin

a proteolytic enzyme that is the principal digestive component of gastric juice. It acts as a catalyst in the chemical breakdown of protein to form a mixture of polypeptides; it is formed from pepsinogen in the presence of acid or, autocatalytically, in the presence of pepsin itself. Pepsin also has milk-clotting action similar to that of rennin and thereby facilitates the digestion of milk protein.

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pepsin barrier

the gastric mucosal mechanism which prevents rediffusion of hydrochloric acid back into gastric tissues; includes an electrical resistance, mucus, plus bicarbonate ions trapped in the mucus, endogenous prostaglandins.