Pelger-Huët anomaly

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Pelger-Huët anomaly

[pel′gər hyo̅o̅′ət]

Etymology: Karel Pelger, Dutch physician, 1885-1931; G.J. Huët, Dutch physician, 1879-1970; Gk, anomalia, irregular

an inherited disorder characterized by granulocytes with unusually coarse nuclear material and dumbbell-shaped or peanut-shaped nuclei. Normal nuclear segmentation does not seem to occur, but there are no associated findings. See also band.

Pelger-Huët anomaly

an anomaly, probably inherited, of neutrophils and eosinophils in which there is hyposegmentation of the nuclei. Seen rarely in dogs and cats with no clinical significance.

pseudo-Pelger-Huët anomaly-H. a

a transient hyposegmentation in neutrophils and eosinophils, usually from unknown causes. May be mistaken as the congenital anomaly.

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