GSK will pay about $1 billion in penalties to the federal government for the illegal promotion of Avandia, Wellbutrin, and Paxil
His group initially suspected that personality changes during treatment with SSRIs (short for selective serotonin reuptake inhibitors) such as Paxil
are a result of alleviating depression.
Shortly after Jake refilled his second Paxil
prescription, he committed suicide by gunshot.
Overall the letter defends Paxil
by showing that SSRIs with longer half-lives, like Prozac, also leave patients with discontinuation symptoms when the patient stops taking them.
A strong performance from key drivers such as asthma treatment Advair is expected to offset a negative impact from sales of Paxil
CR and Wellbutrin, hit by generic competition.
An inspection had found Paxil
tablets could split apart, allowing patients to take a portion that lacked the active ingredient or the controlled-release element, while some Avandamet tablets were discovered to contain the wrong doses of their active ingredient.
However, Glaxo disclosed that sales of Paxil
fell 39 per cent to pounds 1.
Excluding sales of Wellbutrin and Paxil
, turnover grew 10% in the US and 7% globally.
In early June, The New York Times reported that federal regulators are "scrambling to reassess the effectiveness and safety of antidepressants like Paxil
, after British regulators touched off a controversy last year by asking drug companies for unpublished data from antidepressant trials.
DRUG GIANT GlaxoSmithKline knew that the antidepressant Paxil
(sold under the trade name Seroxat in the UK) could not be proved to work on children in 1998, according to a leaked internal document, the BBC reported in February.
According to the FDA, no evidence exists that Paxil
is effective in children or adolescents with major depressive disorder (MDD), and Paxil
is not currently approved in the United States for use in children and adolescents.
I take Coumadin, Lopressor, Paxil
, Norvasc, and Cozaar.