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pargyline

   Also found in: Wikipedia 0.01 sec.
pargyline
a monoamine oxidase inhibitor, used as the hydrochloride salt.

pargyline
Eutonyl Pharmacology An MAOI with antidepressant activity; it is less effective than TCAs; it requires abstinence from foods with tyramine; interacts metabolically with other drugs; its use is limited to Pts unresponsive to TCAs and tetracyclic antidepressants and Pts with atypical depression. See Monoamine oxidase inhibitor, Tricyclic antidepressants.


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Isoform-specific irreversible inhibitors include clorygline, which is a research compound specific for MAO-A, and the two B-selective inhibitors selegiline and pargyline.
50] values of positive control, L-deprenyl (an MAO-B inhibitor) and pargyline (a nonselective MAO inhibitor), were 0.
 
 
 
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