Immunotactoid keratopathy: A clinicopathologic case report and a review of reports of corneal involvement in systemic paraproteinemias
Hemostatic complications associated with paraproteinemias
Once diagnosis is reached treatment is generally initiated to target any underlying diseases that include inflammatory bowel disease gammopathies paraproteinemias leukemias Behcet disease Sweet syndrome hepatitis HIV systemic lupus erythematosus and vasculitides.
In most cases PG is associated with systemic diseases like inflammatory bowel disease inflammatory polyarthritis and hematological disorders as paraproteinemia and leukemias.
Other causes of peripheral neuropathy, such as diabetes, alcoholism, metabolic diseases, intoxications, hereditary neuropathies, HIV, HTLV 1 or 2, vasculitis, paraproteinemias
and other primary or secondary PNS diseases were also ruled-out.
can develop similar lesions (known as necrobiotic xanthogranuloma) that are associated with elevated blood levels of paraproteins.
Secondary factors that worsen hypertriglyceridemia include poor diet, obesity, alcohol use, diabetes, renal disease, pregnancy, nonalcoholic fatty liver disorder, paraproteinemias
, autoimmune disorders, and certain medications, such as steroids.
La disminucion temprana de la via clasica se puede ver en ciertas paraproteinemias
There is extensive coverage of cancer immunology, immunotherapy, immunopharmacology, and immunological aspects of transplantation, paraproteinemias
, and the lymphoreticular system.
TABLE 1 Relatively common acquired polyneuropathies with autonomic nervous system involvement Diabetes mellitus Amyloidosis Guillain-Barre syndrome Paraneoplastic neuropathy (usually small cell lung cancer) Sjogren's syndrome--associated neuropathy TABLE 2 Common blood tests for the evaluation of a distal, symmetrical neuropathy (1,3,5,6,8) TEST POTENTIAL CONFIRMATORY VALUE OF TESTS Fasting glucose or 2-hour Diabetes mellitus and possibly impaired oral glucose tolerance glucose tolerance ("pre-diabetes") test cause neuropathy Serum protein Paraproteinemias
, including monoclonal electrophoresis gammopathy of undetermined significance, Waldenstrom's macroglobulinemia, and osteosclerotic myeloma, are often associated with a demyelinating neuropathy.
Anti phospholipid antibodies, malignancies and paraproteinemias
Increased free fatty acids did not interfere, whereas paraproteinemias
gave discrepant results in some samples compared with the PTA procedure.