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Papanicolaou test

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Papanicolaou test
n.
See Pap smear.

Papanicolaou (Pap) test
[pap′ənik′əlou′]
Etymology: George N. Papanicolaou, Greek physician in U.S. practice, 1883-1962
a simple smear method of examining stained exfoliative cells. It is used most commonly to detect cancers of the cervix, but it may be used for tissue specimens from any organ. A smear, the Papanicolaou's (Pap) smear, is usually obtained during a routine pelvic examination annually beginning at 18 years of age. The technique permits early diagnosis of cancer and has contributed to a lower death rate from cervical cancer. The findings are usually reported descriptively. Also called
Usage notes: (informal)
Pap smear, Pap test.

Papanicolaou test (smear) [pap″ah-nik″o-la´oo]
a simple, painless test used most commonly to detect cancer of the uterus and cervix; it is based on the discovery by Dr. George N. Papanicolaou (1883–1962) that malignant uterine tumors slough off cancerous cells into surrounding vaginal fluid. Called also Pap test and Pap smear.

The Papanicolaou technique, an exfoliative cytological staining procedure, is used also in diagnosis of lung, stomach, and bladder cancers. It can be performed on any body excretion (urine, feces), secretion (sputum, prostatic fluid, vaginal fluid), or tissue scraping (as from the uterus, cervix, or stomach). The sample is removed from the area being examined, placed on a glass slide, stained, and then studied under a microscope for evidence of abnormal or cancerous cells.

In five minutes the Pap test can reveal uterine or cervical cancer at a stage in which it produces no visible symptoms, has done no damage, and usually can be completely cured. It is recommended that all women over age 18, and younger women who have been sexually active, should have an annual Pap test and pelvic examination.
Pap smear. From Lammon et al., 1995.


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Hewitt M, Devesa S and Breen N, Papanicolaou test use among reproductive-age women at high risk for cervical cancer: analyses of the 1995 National Survey of Family Growth, American Journal of Public Health, 2002, 92(4):666-669.
We recently studied a ThinPrep Papanicolaou test (Cytyc Corporation, Boxborough, Mass) from a 51-year-old woman with a history of exposure to diethylstilbestrol who was 3 years postmenopausal and on hormone replacement therapy.
Between 1990 and 2002, Barbara Fordham underwent annual gynecological exams that included the Papanicolaou test, also known as the Pap test or Pap smear, which is used to diagnose abnormalities of cells from the cervix.
 
 
 
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