PANK1

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PANK1

A gene on chromosome 10q23.31 that encodes a member of the pantothenate kinase family, which are key enzymes in coenzyme A (CoA) synthesis. PANK1 catalyses the first and rate-limiting enzymatic reaction in CoA biosynthesis and is regulated by CoA through feedback inhibition.
References in periodicals archive ?
The enzyme, called pantothenate kinase, triggers the first step in the production coenzyme A, a molecule indispensable to all forms of life.
The company also plans to advance RE-024 for Pantothenate Kinase Associated Neurodegeneration (PKAN), as well as RE-001, for Duchenne Muscular Dystrophy.
Jude, has conducted extensive research on coenzyme A, which is regulated by pantothenate kinase.