PANK1

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PANK1

A gene on chromosome 10q23.31 that encodes a member of the pantothenate kinase family, which are key enzymes in coenzyme A (CoA) synthesis. PANK1 catalyses the first and rate-limiting enzymatic reaction in CoA biosynthesis and is regulated by CoA through feedback inhibition.
References in periodicals archive ?
The other group with predominant deep gray matter involvement are two cases of Wilson's disease and two cases of Pantothenate Kinase deficiency.
Two cases of Pantothenate Kinase deficiency (Hallervorden-Spatz disease) were noted showing T2WI/FLAIR hyperintensity with surrounding hypointensity in bilateral globus pallidus noted.
The company also plans to advance RE-024 for Pantothenate Kinase Associated Neurodegeneration (PKAN), as well as RE-001, for Duchenne Muscular Dystrophy.
1) The sign is considered as the distinctive radiologic feature of Neurodegeneration with Brain Iron Accumulation (NBIA) type 1, also known as Pantothenate Kinase Associated Neurodegeneration (PKAN).
The sign is considered the distinctive radiologic feature of Neurodegeneration with Brain Iron Accumulation (NBIA) type 1, also known as pantothenate kinase associated neurodegeneration (PKAN).
Hallervorden Spatz disease also known as Pantothenate Kinase 2 associated neurodegeneration (PKAN), is a rare autosomal recessive condition [1].
The gene for the coding of pantothenate kinase is recently identified on chromosome 20p.
Jude, has conducted extensive research on coenzyme A, which is regulated by pantothenate kinase.