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pancuronium bromide

   Also found in: Wikipedia 0.01 sec.
pancuronium bromide
[pan′kyərō′nē·əm]
a skeletal muscle relaxant; a nondepolarizing neuromuscular blocker.
indications It is prescribed as an adjunct to anesthesia and mechanical ventilation.
contraindications Known hypersensitivity to this drug or to other bromides prohibits its use. Ventilation always must be supported during the use of neuromuscular blockers. Patients with renal and hepatic disease require dosage adjustments, and pancuronium is not recommended during pregnancy. Some diseases (e.g., myasthenia gravis) can potentiate the effects of pancuronium, whereas others (e.g., diabetes mellitus) can antagonize the drug's effects.
adverse effects The most serious adverse effects are prolonged muscle relaxation and respiratory depression.

pancuronium bromide, (pang´kyrō´nēm brō´mīd),
n a skeletal muscle relaxant prescribed as an adjunct to anesthesia and mechanical ventilation.


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It is the pancuronium bromide that is controversial.
Jay Chapman, suggested using a three-drug protocol: "sodium thiopental as the barbiturate sedative, to induce unconsciousness; pancuronium bromide as a neuromuscular blocking agent, to induce paralysis; and potassium chloride, to induce cardiac arrest.
Almost all the states use the same three-drug combination: sodium pentothal, to render the inmate unconscious; pancuronium bromide, to paralyze all skeletal muscles; and potassium chloride, to stop the heart and cause death.
 
 
 
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