Pancoast syndrome

Pan·coast syndrome (pnkst)

n.

A syndrome characterized by pain and tingling of the arm, constriction of the pupil, and paralysis of the elevator muscle of the upper eyelid, caused by pressure on the brachial plexus resulting from invasion of a malignant tumor in the apex of the lung.

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Pancoast syndrome

Oncology A syndrome characterized by a malignant neoplasm–Pancoast's tumor–of the cervical region with destruction of the thorax inlet and involvement of the brachial plexus and cervical sympathetic nerves, accompanied by severe pain in the shoulder region radiating toward the axilla and scapula along the ulnar aspect of hand muscles, atrophy of hand and arm muscles, Bernard-Horner syndrome, and compression of blood vessels with edema; PS may be found in inflammatory pseudotumor and in mycotic aneurysms. See Pancoast tumor.