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pamidronate

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pamidronate /pam·i·dro·nate/ (pam″ĭ-dro´nāt) an inhibitor of bone resorption used to treat malignancy-associated hypercalcemia, osteitis deformans, and osteolytic metastasis secondary to breast cancer or myeloma; used as the disodium salt. Complexed with technetium 99m, it is used in bone imaging.
pamidronate [pam″ĭdro´nāt]
an inhibitor of bone resorption, used to treat malignancy-associated hypercalcemia, Paget's disease of bone, and osteolytic metastasis secondary to breast cancer or myeloma; used as the disodium salt. Complexed with technetium 99m it is used in bone imaging.

pamidronate
Aredia® Metabolism A 2nd-generation biphosphonate used to manage osteoporosis and Paget's disease of bone. See Biphosphonate, Osteoporosis.


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Recommendations have been made to use either pamidronate or zoledronic acid every 3 to 4 weeks in patients who have one or more lytic lesions on skeletal roentgenograms.
Food and Drug Administration has granted approval for an Abbreviated New Drug Application (ANDA) for Pamidronate Disodium Injection, 3 mg/mL and 9 mg/mL in 10 mL vials.
1) Formerly, only intravenous agents such as pamidronate were available.
 
 
 
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