NLRP7

(redirected from PYPAF3)

NLRP7

A gene located on chromosome 19q13.42 that encodes a member of the NACHT protein family, which is thought to act as a feedback regulator, inhibiting caspase-1-dependent interleukin 1-beta secretion.
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PYPAF3, aPYRIN containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion.