ABCC6

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ABCC6

ATP-binding cassette sub-family C (CFTR/MRP) member 6. A gene on 16p13.1 that encodes a protein of the superfamily of ATP-binding cassette (ABC) transporters, which transport various molecules across extra- and intra-cellular membranes.

Significance
The encoded protein is involved in multi-drug resistance; mutations in ABCC6 cause pseudoxanthoma elasticum.
References in periodicals archive ?
About 10% of PXE sufferers develop problems with gastrointestinal bleeding, but it would be unusual to have life-threatening episodes.
In the PXE patients, earlier disease onset was observed for homozygous carriers of this allele.
Though nephrocalcinosis was a chance finding in our case, this could enable an early diagnosis of PXE, with timely modification of potential risk factors and close monitoring of renal function.
The association of each polymorphism with PXE was measured by the odds ratio (OR) and 95% CI.
PXE is histologically characterized by progressive calcification of elastic fibers and massive accumulation of proteoglycans in the extracellular matrix (24-26).
You can create a Windows operating system image in order to boot Windows via PXE.
The PXE gene has recently been found to encode for ABCC6/MRP6, a protein that belongs to the ABC family of membrane transporters (20-22).
Available with Devon Terminal Operating System (DeTOS), Windows XP Embedded (XPe) or PXE boot
The NTA 6020 line of thin client terminals - available with the Devon Terminal Operating System (DeTOS), Windows XP Embedded (XPe), or PXE boot - delivers reliability, security, and performance features.
MISSISSAUGA, ON, May 12 /PRNewswire/ -- Argon Technology announces the global release of their popular PXE on Disk(TM) product to support network adapters using Realtek RTL8169S Gigabit Ethernet controller.
With the new manageable PXE (Preboot Execution Environment) enabled adapter installed on their notebooks, IT departments can use PXE based software to remotely manage them.