PUM1

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PUM1

A gene on chromosome 1p35.2 that encodes a sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. PUM1 may support stem cell proliferation and self-renewal by regulating translation of key transcripts. It is expressed in the brain, heart, kidneys, muscle, intestine and stomach and downregulated in keratinocytes in response to UVB irradiation.
References in periodicals archive ?
Supper adds, "Through our affiliation with ACTS, we have significantly more buying power than the four facilities chat were PUMH.
The contracts of new PUMH residents moving in post-affiliation also changed to ACTS contracts.