PUFA


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PUFA

polyunsaturated fatty acid.

PUFA

(pŭf′ə, po͞o′fə, pē′yo͞o′ĕf′ā′)
abbr.
polyunsaturated fatty acid

PUFA

abbreviation for polyunsaturated fatty acid. See unsaturated fatty acid.

polyunsaturated fat

A saturated fatty acid (i.e., an alkyl-chain fatty acid) with two or more ethylenic carbon–carbon double bonds; because of the double bond, not every carbon is saturated with hydrogen atoms—i.e., there are fewer hydrogens—which reduces the strength of the compound's intermolecular forces, resulting in a significant lowering of the compound’s melting point.

Polyunsaturated fats in humans
• Linoleic PFAs—two double bonds between 9/10 (Δ9) and 12/13 (Δ12); e.g., CnH2n-COOH.
• Linolenic PFAs—three double bonds, Δ9, Δ12, Δ15; e.g., CnH2n-5-COOH.
• 4-doubled bond PFAs—four double bonds, Δ5, Δ8, Δ11, Δ14; e.g., arachidonic acid.

PUFA

polyunsaturated fatty acids

PUFA

polyunsaturated fatty acids.
References in periodicals archive ?
This suggested that the supplementation of oil mixtures rich in PUFA had strongly inhibited the de novo synthesis of FA in mammary fat tissues, because almost milk C4:0-C14:0 and about half of C16:0 are synthesized de novo by the mammary epithelial cells.
Extraction yields of total lipid extract, total FAs, and PUFAs were analyzed by 1-way unequal variance (Welch) ANOVA because the assumption of normality is not critical for equal sample sizes.
Significant heterogeneity was noted on the analysis of blood level n-3 PUFA DHA and EPA with total prostate cancer risk and high-grade prostate tumours (Table 2.
Rheumatoid arthritis is one of many other autoimmune diseases for which PUFA supplements have made a difference.
An elegant study by Storlein et al (8) showed that replacement of as little as 6 per cent [omega]-6 PUFAs (safflower oil) with long chain (LC) [omega]-3 PUFAs (fish oil) was able to prevent the development of insulin resistance.
It was shown that if there is a lot of PUFA in the diet, vitamin E alone cannot protect fully from the oxidation.
So in these patients pharmacological therapy is commonly based on statins, fibrates or n-3 PUFA with a good efficacy and safety of use.
9 years of follow-up was 27% in the n-3 PUFA group and 29% in controls, for a significant adjusted 9% relative risk reduction in the n-3 PUFA group, reported Dr.
It can be concluded that [omega]-3 PUFA supplementation offers a means of augmenting cancer therapy, inhibiting tumourigenesis and possibly contributing to cachexia alleviation.
PUFA supplementation has been shown to reduce renal inflammation and fibrosis in animal models (6).