PRDM1

PRDM1

A gene on chromosome 6q21 that encodes a protein which represses beta-interferon gene expression, by binding to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. PRDM1 transcription increases in response to viral induction.
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Cells with the protective version of both markers expressed PRDM1 after being exposed to radiation.
Previous studies have found that PRDM1 is involved in a variety of fundamental cellular processes, including proliferation, differentiation and apoptosis -- which can all go awry in cancer.