progressive pseudorheumatoid arthropathy of childhood

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progressive pseudorheumatoid arthropathy of childhood

An autosomal recessive disorder (OMIM:208230) characterised by stiffness and swelling of joints, motor weakness and joint contractures of early (between age 3 and 8) onset in which there is progressive cartilage loss and bone destruction with age.

Molecular pathology
Defects of WISP3, which encodes a connective tissue growth factor essential for normal postnatal skeletal growth and cartilage homeostasis, cause progressive pseudorheumatoid arthropathy of childhood.
References in periodicals archive ?
The PPAC annual report also covers topics including finance, IT, budget, legislation, and the overall state of the patent system, and makes recommendations for improvements at the PTO.
It's been a major, major headache in our office and they're still trying to get those numbers," said PPAC member Dr.
The SCoP complaint which was extended to Sudan Tribune on Wednesday said that constitutional and legal rights of its members and leadership have been violated; pointing the party is registered according to the PPAC regulations.
PPAC members asked CMS officials to keep in mind that physicians who improve quality and lower costs should also be credited for savings that may show up as reduced hospital spending due to preventive screening or disease management services provided in doctors' offices.
In another avenue for addressing low physician reimbursement, the PPAC asked CMS for a report on whether Medicare Part B drugs could be removed retrospectively, using an administrative methodology.
Stack says that members of PPAC will make regular visits to select congressional leaders and others in the executive branch who formulate security-related government and law enforcement policy.
The inclusion is duplicative and unfair to physicians not participating in the CAP, the PPAC determined.
However, the PPAC, on Sunday, rejected NISS's request, saying it must be proven that the NUP had effectively violated the constitution as it claimed by the NISS.
He acts pro-choice," said Kathy Kneer, president and CEO of PPAC.
ASP is sort of this moving target," since it's not clear how CMS will define it, noted PPAC member Dr.
Edward Hill, immediate past chairman of the board of trustees of the American Medical Association, told PPAC members, because a drug is not a physician service.
The PPAC said the RP's registration request violated provisions of Article (1/5) of the 2005 interim constitution and Article (14) of the 2007 Political Parties' Act.