POEMS syndrome


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Related to POEMS syndrome: Castleman's disease

POEMS syn·drome

a condition characterized by polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes.

POEMS syndrome

a multisystem syndrome combining polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes. It may be linked to a dysproteinemia such as the presence of unusual monoclonal proteins and light chains. Also called Crow-Fukase syndrome, PEP syndrome.

POEMS syndrome

Crow-Fucase syndrome A multisystem disease characterized by an acronym, POEMS, derived from Polyneuropathy–distal symmetric progressive muscle weakness, paresthesias, ↓ nerve conduction velocity; Organomegaly–hepatosplenomegaly, lymphadenopathy; Endocrinopathy–hirsutism; Monoclonal gammopathy–myeloma and focal osteosclerosis

POEMS syn·drome

(pōĕmz sindrōm)
A condition characterized by polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes.
Synonym(s): Crow-Fukase syndrome.

POEMS syndrome

A SYNDROME named as an acronym for Polyneuropathy (a disorder of peripheral nerves), Organomegaly (enlarged organs-liver and spleen), Endocrinopathy (endocrine gland hormonal disorders), M-proteins (Monoclonal IMMUNOGLOBULIN increase) and Skin changes (pigmentation, thickening, sweating, hairiness and FINGER CLUBBING). The condition is rare in Britain but many cases have been reported in Japan.

POEMS syn·drome

(pōĕmz sindrōm)
Condition characterized by polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes.
References in periodicals archive ?
Severe polyneuropathy: initial manifestation of Castleman's disease associated with POEMS syndrome.
Marked recovery of severe renal lesions in POEMS syndrome with high dose melphalan therapy supported by autologous blood stem cell transplantation.
Dramatic improvement of POEMS syndrome following autologues haematopoietic cell transplantation.