PIE Syndrome

PIE Syndrome

A heterogeneous group of conditions characterised by intense, nonspecific symptoms accompanied by chronic relapsing fever, cough and shortness of breath, and chronic eosinophilia in the blood or tissue. Some authors divide these into those caused by inhaled or ingested extrinsic factors—e.g., medications and pathogens, especially parasites—and those attributed to intrinsic factors which are usually idiopathic in nature and often linked to autoimmunity

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PIE syndrome

pulmonary infiltration with eosinophilia; a disease of dogs of unknown origin characterized by dyspnea, reduced exercise tolerance, diffuse pulmonary infiltration by eosinophils and an eosinophilia.

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PIE syndrome

Pulmonary infiltrates with eosinophilia A condition characterized by intense, nonspecific Sx accompanied by chronic relapsing fever, cough and SOB, associated with chronic eosinophilic pneumonia

PIE syndrome

Simple PIE Löffler syndrome Transient pulmonary infiltrates fever, dyspnea, eosinophilia of peripheral blood

Tropical eosinophilia Associated with microfilarial parasites–eg, Ascaris lumbricoides and Toxocara canis

Secondary chronic pulmonary eosinophilia Associated with allergic bronchopneumonia related to aspergillosis, bronchocentric granulomatosis, allergic angiitis and granulomatosis–Churg-Strauss syndrome, drugs–nitrofurantoin, sulfonamide, and infections–parasitic, fungal, and bacterial