PICO

PICO,

n acronym for diagnostic questions based on these four areas of knowledge and action: Patient or problem;
Intervention, cause, or prognosis;
Comparison or control; and
Outcome. This evidence-based method is designed to make a valid, successful decision based on the skills and knowledge of the clinician, the values of the patient, and the best available evidence.

Picornaviridae

n one of the major ribonucleic acid virus families, to which the polio-, rhino-, entero-, and hepatitis A viruses belong. Viruses in this family have a single-stranded, nonsegmented, linear molecular structure with icosahedral symmetry.