properdin /pro·per·din/ (pro´per-din) factor P; a nonimmunoglobulin gamma globulin component of the alternative pathway of complement activation.
properdin [pro´per-din]
pro·per·din (pr -pûr dn)n. A natural protein in human blood serum that participates in the body's immune response by working in conjunction with the complement system. |
properdin [pro´per-din]
a protein of the alternative complement pathway, augmenting complement activation. Called also factor P.
properdin
a normal, relatively heat-labile, nonantibody serum protein (a euglobulin) that, in the presence of complement component C3 and magnesium ions, is involved in the alternative complement pathway, and acts nonspecifically against gram-negative bacteria and viruses and plays a role in lysis of erythrocytes. It may act in conjunction with complement-fixing antibody.
properdin pathway
alternative complement pathway.
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