PF4

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PF4

A gene on chromosome 4q12-q21 that encodes a protein released from the alpha-granules of activated platelets which binds with high affinity to heparin. PF4’s major physiologic role appears to be neutralisation of heparin-like molecules on the endothelial surface of blood vessels, inhibiting antithrombin-III activity and promoting coagulation; as a chemoattractant for neutrophils and fibroblasts, PF4 likely plays a role in inflammation and wound repair.
References in periodicals archive ?
Peshawar, October 26, 2010 (Balochistan Times): A delegation of union council secretaries of PF-4 called on the Khyber Pakhtunkhwa Minister for Sports, Culture and Tourism Syed Aqil Shah at the latters office Qayyum Stadium Peshawar on Tuesday.
Peshawar, October 26, 2010 (Frontier Star): A delegation of union council secretaries of PF-4 called on the Khyber Pakhtunkhwa Minister for Sports, Culture and Trousim Syed Aqil Shah at the latter's office Qayyum Stadium Peshawar on Tuesday.
PESHAWAR, November 07, 2009 (Balochistan Times): NWFP Minister for Sports, Culture and Tourism Syed Aqil Shah has said that the use of sub-standard material in the construction of different roads as well as other development schemes in PF-4 will not be tolerated.