PELD score

PELD score

[Acronym for pediatric end-stage liver disease]
A tool for characterizing the severity of liver disease in pediatric patients (under 12 ), used to determine their priority for receipt of donor organs. Patients with higher scores (more severe disease) are given a higher priority for transplantation. The score is based on repeated measurements of five variables: the patient's age, serum albumin level, serum bilirubin level, INR (international normalized ratio), and growth failure, entered into the following equation: PELD score = 0.436 (if patient is listed before age 1 year) — 0.687Ln(serum albumin) + 0.480LN(serum bilirubin) +1.857LN(INR) +0.667(for growth failure that is more than 2 standard deviations below normal).
References in periodicals archive ?
1 hospital and transplantation (months) PELD score during transplantation 21 (15-36) 29 (21-45) Growth rate during transplantation Below 3rd percentile 4 10 Between 3rd and 10th percentiles 7 10 Between 10th and 25th percentiles 8 2 Over 25th percentile 9 - Institutes p Transplantation time (months) <.
Significant differences were observed in the age at transplantation, duration between KPE and transplantation, and PELD scores between patients with BA who underwent KPE at our center and who underwent KPE at other institutes from other institutes.
There were significant differences in the age at transplantation, time between KPE and transplantation, and PELD scores between patients with BA who underwent KPE at our center and those patients from other institutes (p<0.
The PELD score, derived from bilirubin, albumin, INR, growth failure and patient age when first placed on the waiting list, may be calculated with a tool available on the United Network for Organ Sharing (UNOS) website.
The PELD score has not been proven to be a successful predictor of post-transplantation outcome, but has also not been shown to adversely affect results.
PELD score and posttransplant outcome in pediatric liver transplant: A retrospective study of 100 recipients.
OPTN policy prioritizes liver candidates local to the organ donor with a MELD or PELD score of 15 or higher, than those candidates within the region of the donor who have scores 15 or higher, before any less urgent candidates may be considered.
Of candidates listed in the United States with an initial MELD or PELD score between19 and 24, half receive a liver transplant within approximately 15 weeks of being listed.
The higher the MELD or PELD score, the greater the risk of dying from liver disease.
The status 1 category has remained in place as the highest priority for receiving an organ and is not affected by the MELD or PELD scores.
MELD and PELD scores are considered more accurate than the Child-Pugh score in determining short-term mortality, (16) and are used by the United Network of Organ Sharing (UNOS) for liver allocation.