PELD score

PELD score

[Acronym for pediatric end-stage liver disease]
A tool for characterizing the severity of liver disease in pediatric patients (under 12 ), used to determine their priority for receipt of donor organs. Patients with higher scores (more severe disease) are given a higher priority for transplantation. The score is based on repeated measurements of five variables: the patient's age, serum albumin level, serum bilirubin level, INR (international normalized ratio), and growth failure, entered into the following equation: PELD score = 0.436 (if patient is listed before age 1 year) — 0.687Ln(serum albumin) + 0.480LN(serum bilirubin) +1.857LN(INR) +0.667(for growth failure that is more than 2 standard deviations below normal).
References in periodicals archive ?
The PELD score, derived from bilirubin, albumin, INR, growth failure and patient age when first placed on the waiting list, may be calculated with a tool available on the United Network for Organ Sharing (UNOS) website.
The PELD score has not been proven to be a successful predictor of post-transplantation outcome, but has also not been shown to adversely affect results.
OPTN policy prioritizes liver candidates local to the organ donor with a MELD or PELD score of 15 or higher, than those candidates within the region of the donor who have scores 15 or higher, before any less urgent candidates may be considered.
Of candidates listed in the United States with an initial MELD or PELD score between19 and 24, half receive a liver transplant within approximately 15 weeks of being listed.
The revised policy changes the allocation sequence for patients with a MELD or PELD score of 15 or higher.
Currently, approximately 80 percent of liver recipients have a MELD or PELD score of 15 or greater at the time of their transplant.