PC-SPES

PC-SPES

(pē-sē-spēs′)
A mixture of herbs (chrysanthemum, Ganoderma lucidum, isatis, licorice, Panax pseudo-ginseng, Rabdosia rubescens, saw palmetto, and scutellaria) with estrogen-like effects. The mixture was formerly promoted as an alternative therapy for prostate cancer. It has been taken off the market in the U.S. because of contamination and adulteration with pharmaceuticals.
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Prospective, multicenter, randomized phase II trial of the herbal supplement, PC-SPES, and diethylstilbestrol in patients with androgen-independent prostate cancer.
Herbal products may even be adulterated with prescription drugs, as recently reported for the Chinese herbal formula PC-SPES (2).
The product, called PC-SPES, has since been recalled by its California-based manufacturer, BotanicLab, which has gone out of business.
The report describes various natural sources of spindle poisons, including colchicine, curacin, combretastatins, cryptophycins, discodermolide, dolastatin, auristatin PHE, symplostatin 1, epothilones, eleutherobin, halichondrin B, halimide, hemiasterlins, laulimalide, maytansinoids, PC-SPES, peloruside A, resveratrol, S-allylmercaptocysteine (SAMC), spongistatins, taxanes, Vinca alkaloids, vitilevuamide, etc.
Researchers are more confident that a mixture of seven herbs called PC-SPES may slow advanced cancer in men who have no other treatments available.
PSA levels in the hormone dependent men fell by more than 80 per cent after taking the supplement, known as PC-SPES.
Scientists at the University of California found that the supplement, known as PC-SPES, capsules significantly lower levels of prostate specific antigen (PSA), a protein in the blood closely linked to the cancer.
Doctors from Robert Wood Johnson Medical School in New Jersey tested a mixture of eight herbs, sold as PC-SPES, on men with prostate cancer.
As a result of this, NCCAM is expected to impose stricter standards on products used in research it funds in light of PC-SPES contamination problems.
Chen will discuss the latest findings on PC-SPES -- an herbal treatment for prostate cancer.
The PC-SPES capsule - made from eight Chinese herbs - significantly lowers levels of PSA protein in the blood, which is linked to the cancer.
PC-SPES, a combination of herbs used by men with prostate cancer, has potent estrogen-like activity.