CXCL12

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CXCL12

A gene on chromosome 10q11.1 that encodes a stromal cell-derived alpha chemokine of the intercrine family which, once bound to its receptor, CXCR4, activates lymphocytes, an interaction that has been implicated in the metastasis of breast and other cancers.

Molecular pathology
CXCL12 mutations are associated with resistance to HIV-1 infections.
References in periodicals archive ?
PBSF gives more returns than many other PE investors as it is backed by business strategy and efficiency advantages flowing from PCG," he claimed.
Parmar, who had done his schooling from the Naval School, Goa, invested $ 500 million in PBSF, and raised a similar investment from banks, while the remaining came from debt.
This (dinner) is the ultimate experience for a baseball fan because everybody in that room is somebody,'' said Lisa Jackson, another member of the PBSF and the organization's event producer.
PBSF's mission is to create that financial bridge for scouts in need, and will generate funds through contributions from corporations and individuals, an annual fundraiser, as well as donations of sports memorabilia to be auctioned -- with PBSF receiving 100% of the proceeds.