PAH


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PAH

Abbreviation for p-aminohippuric acid.

PAH

,

PAHA

aminohippuric acid.

pulmonary hypertension, primary, type 1

A rare disorder (OMIM:178600) characterised by plexiform lesions of proliferating endothelial cells in pulmonary arterioles, leading to elevated pulmonary arterial pressure, right ventricular failure and death. The disease can occur at any age from infancy onward, but has a mean age of onset at 36 years. Cases secondary to known aetiologies are the more common cause of pulmonary hypertension, and include those associated with appetite-suppressant drugs.

Molecular pathology
May be caused by defects of SMAD9, which encodes a receptor-regulated SMAD, transducing signals from TGF-beta family members.

PAH

1. Polycyclic aromatic hydrocarbon, see there.
2. Pulmonary artery HTN.
References in periodicals archive ?
4] is elevated in both animal models of PAH as well as human PAH disease and that elevated LTB[sub.
PAH is characterized by morphological changes to the endothelium of the arteries of the lungs causing remodeling of the tissue and vasoconstriction.
This study suggests that exposure to PAH encountered in New York City air may play a role in childhood ADHD," says lead author Frederica Perera, DrPH, PhD, director of the Center and professor of Environmental Health Sciences at the Mailman School.
A complex class of organic compounds containing two or more fused benzene rings in a linear, angular or cluster arrangement, PAHs are generally considered carcinogenic and mutagenic in nature.
Alkane and PAH depositional history, sources and fluxes in sediments from the Fraser River Basin and Strait of Georgia, Canada.
For all validation replicates, measured concentrations of each PAH were generally within 30% of the NIST certified value (maximum error of 55%), and the sum of the PAHs was within 5% of the sum of the NIST certified values.
Past research has tied air pollution to asthma and allergy, but the link between PAHs and these immune problems is still unclear.
PAH is defined as the presence of a mean pulmonary arterial pressure (PAP) that exceeds 25 mmHg at rest or 30 mmHg during exercise.
The relationship between atmospheric PAH concentrations and meteorologic parameters has been extensively studied.
However, these three drugs accounted for only a 24% market share to PAH market in 2005.
It is important to consider that most of studies regarding histopathological properties and proper treatment in PAH have been done in idiopathic PAH.
PAH degradation experiments were performed with the original contaminated soil inoculated into 50 mL serum bottle flasks tightly closed with polypropylene lid and aluminum cap.