P2RY11

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P2RY11

A gene on chromosome 19p13.2 that encodes a G protein-coupled receptor for various drugs as well as adenosine and uridine nucleotides. P2RY1 is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and acts as a selective purinoceptor.
References in periodicals archive ?
ATP gradients inhibit the migratory capacity of specific human dendritic cell types: implications for P2Y11 receptor signaling.
Such patents address targets such as CCR5, Chemerin receptor, GPR43, GPR7/8, purinergic receptors (P2Y4, P2Y11 and P2Y13) and SHIP2 for type II diabetes.
lt; < Family Receptor Type GPCRs < < GPR GPR120 < < Protease Activ- PAR4 < < Lysophospholip- S1P2 (Edg5) < < Urotensin rUT < < Serotonin 5-HT3A < < Glucagon GLP-2 < < Prokineticin PKR2 < < GPR GPR91 < < Glucagon Secretin < < Dopamine D2L < < Purinergic P2Y11 < < GPR GPR1 < < NeuropeptideFF NPFF1 Ion channels < < Voltage gated Kv1.
Such patents include CCR5, GPR7/8 involved in metabolic defects and adult-onset obesity, purinergic receptors (P2Y4, P2Y11 and P2Y13), ORL-1 and the non-GPCR SHIP2 for type II diabetes.