PRPF8

(redirected from P220)
Also found in: Acronyms.

PRPF8

A gene on chromosome 17p13.3 that encodes protein which is a central component of the spliceosome and thought to play a role in aligning pre-mRNA 5'- and 3'-exons for ligation. It interacts with U5 snRNP proteins SNRP116 and WDR57/SPF38, and with EFTUD2 and SNRNP200.

Molecular pathology
Defects in PRPF8 cause retinitis pigmentosa type 13.
References in periodicals archive ?
The P220 operates by a locked-breech, short-recoil action harking back to John M.
In May of last year, my SIG P220 broke during a departmental qualification.
An important observation was that a consistent increment in the roughness values when grit size was increased from a smoother to a coarser grit (from P220 to P100) did not exist and was believed to be due to variability in the wood properties.
The P220, made by the US-based Sigarms company, is the "weapon of choice" of elite units worldwide.
Announced today are the P220 and P230 devices in the Petra family, providing 40Gbps and 80Gbps full-duplex traffic management and fabric access functionality, respectively.
In the late 1970's, SIG SAUER contracted with Browning to produce their P220 pistol as the Browning BDA, and it caught the imagination of American shooters.
22 conversion units for their popular P226 and P220, consumer interest has been brisk.
She popped into a Sainsbury's store to use its disabled toilet, removed her holster containing the deadly Sig Sauer P220 gun and placed it on the cistern.
MorethanIP's offering of SPAUI and RXAUI IP cores was tested and validated with Dune's new generation of FAP devices, called the PETRA family, which includes the P220, P230, and P130 devices.
Limited Tenders are invited for Supply of Micom P220 Relay Battery