tosyl

(redirected from P-toluenesulfonyl)

to·syl

(tō'sil),
Toluenesulfonyl radical, widely used to block amino groups in the course of organic syntheses of drugs and other biologically active compounds.
References in periodicals archive ?
Fabrication of HPC-mefenamic acid conjugates was achieved by using p-toluenesulfonyl chloride as carboxylic acid (a functional group in drug) activator at 80C for 24 h under nitrogen atmosphere.
Imidazole and p-toluenesulfonyl chloride (Tos-Cl) were obtained from Fluka.
28 g; 30 mmol) was dissolved in 25 mL of 3 mol/L sodium hydroxide, and p-toluenesulfonyl chloride (6.
The HPC-Ibuprofen conjugates as macromolecular prodrugs were therefore synthesized employing homogenous and one pot reaction methodology using p-toluenesulfonyl chloride.
Ibuprofen was in situ activated with p-toluenesulfonyl chloride (Tos-Cl) in N,N-dimethylacetamide (DMAc) containing pre- dissolved HPC [19].