OvHV-2

OvHV-2

ovine herpesvirus-2, a Rhadinovirus in the subfamily Gammaherpesvirinae. It is the sheep-associated malignant catarrhal fever virus transmitted to cattle from sheep.
References in periodicals archive ?
Here we describe OvHV-2 DNA in the blood and semen of asymptomatic boars and from the brain of symptomatic sows and gilts with MCF that was probably transmitted by artificial insemination.
OvHV-2 DNA was detected by using a specific PCR (4) in 5 of 7 paraffinized sections of the brainstem (5).
To find possible carriers of the virus, blood samples were collected from 9 pregnant sows, 10 nonpregnant sows, and 30 breeding boars and analyzed for OvHV-2 DNA.
Our findings of OvHV-2 DNA in the semen of asymptomatic boars suggest that the OvHV-2 in the sows and gilts originated from asymptomatic boars that were responsible for maintaining the virus in the herd.
Emergence of OvHV-2 in boars that had no known contact with sheep was surprising, especially given the possibility of venereal transmission through contaminated semen.
Malignant catarrhal fever in free-ranging cervids associated with OVHV-2 and CPHV-2 DNA.
The vasculitis lesions were strikingly similar to those observed in cattle with MCF caused by OvHV-2 or alcelaphine herpesvirus 1.
Although horses are not considered susceptible to OvHV-2, histopathologic findings in this case were consistent with MCF-like lesions.
DNA was extracted from these samples, and PCR was performed to detect members of the MCFV group, including OvHV-2 (5), caprine herpesvirus 2 (6), and alcelaphine herpesvirus 1 (7).
Considering that sheep and goats are the most important natural reservoirs of OvHV-2 (6), these results support the notion that infected goats were the most likely source of infection for horses in this outbreak.
To further support this diagnosis of OvHV-2 infection, we attempted to detect viral DNA in the vascular wall of the foal's hepatic arterioles that contained fibrinoid necrotizing lympho-histiocytic vasculitis by using laser capture microdissection on sections stained with hematoxylin and eosin (10).