Osteolytic lesion

Osteolytic lesion

Soft spot or hole in bone caused by cancer cells.
Mentioned in: Multiple Myeloma
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In the one case of desmoplastic fibroblastoma of bone, the X-ray of the right proximal femur showed an osteolytic lesion with a well-defined sclerotic rim, but lack of matrix calcification [Figure 1]b.
4) Aneurysmal bone cyst is an expansile, multilocular, osteolytic lesion with blood-filled spaces separated by fibrous septa containing multinucleated giant cells and peripheral reactive bone.
Hypercalcaemia in plasma cell leukaemia is profound with extensive osteolytic lesion.
Chromoblastomycosis with underlying osteolytic lesion.
As a result, some metal debris remained inside the retroacetabular osteolytic lesion, leading to expansion of the osteolysis along with diffusion around the periacetabular soft tissue, for example, into the intrapelvic space.
Caption: Figure 6: AP radiograph of the right knee shows significant progression of the tibial plateau osteolytic lesion in the medial tibial plateau, which now extends to the epiphysis.
A CT scan was obtained in this case, which revealed contained osteolytic lesion with flaky sequestrum in patella (Fig.
The other treatment modalities include bisphosphonates as reported other authors10,11 following benefits like reduction in pain and inflammatory symptoms with increased osseous density and recalcification of osteolytic lesion.
The latter is a nonneoplastic, single to multifocal, osteolytic lesion initially described in the jaw, but now recognized in almost all bones, including lower and upper extremity long tubular bones (see following section for theoretical consideration).
Histopathologic examination of the osteolytic lesion showed a bone tumor with vascular stroma, spindle-shaped stromal cells, and multinucleated giant cells, demonstrating GCT of the right radius.
EMP is a soft tissue plasma cell tumor occurring in the absence of systemic signs of multiple myeloma, such as a bone osteolytic lesion, plasma cell infiltration in bone marrow, a lytic bone lesion, and serum or urine myeloma proteins (1) .
Chest radiographs revealed pleural thickening underlying a soft tissue mass which obscured the 5th to 7th ribs, and an expansile osteolytic lesion of the 7th rib.