osmium tetroxide

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os·mic ac·id

(oz'mik as'id),
OsO4; a volatile caustic and strong oxidizing agent; colorless crystals, poorly soluble in water, but soluble in organic solvents; the aqueous solution is a fat and myelin stain and a general fixative for electron microscopy.
Synonym(s): osmium tetroxide

osmium tetroxide

n.
A volatile poisonous pale yellow solid, OsO4, with a pungent smell, used as an oxidizing agent and in solution to stain and fix biological material, especially lipids. Also called osmic acid.

osmium tetroxide

or

osmic acid

a substance used in the fixing of cytological preparations that is characterized by the small amount of distortion it causes.

osmium

a chemical element, atomic number 76, atomic weight 190.2, symbol Os. See Table 6.

osmium tetroxide
a pathology stain and fixative; called also osmic acid.
References in periodicals archive ?
The pellets were washed in Pipes buffer with sucrose for 2 h at 4[degrees]C and postfixed in 1% osmium tetraoxide in Pipes buffer for 75 min at 4[degrees]C.
The specimens were postfixed in 1% osmium tetraoxide for 1 h at room temperature, dehydrated in an ethanol series and acetone, and embedded in Epon resin.
For TEM observations, ultrathin specimens were cut in a vertical direction to the fracture surface and stained with osmium tetraoxide.
5% glutaraldehyde, postfixed in osmium tetraoxide, dehydrated, critical point dried, ion sputtered gold, and examined using a SEM (Hitachi S-570).
To enhance the image contrast of the rubber phase, microtomed sections of GTX 910 were stained at ambient temperature in the vapor of a 2% aqueous solution of osmium tetraoxide, Os[O.
The samples were post-fixed with 1% osmium tetraoxide in the sodium phosphate buffer, washed with distilled water and dehydrated in an ethanol gradient.
The material was fixed with 1% osmium tetraoxide in the 0.
For direct examination of the two phase nature of a rubber-modified epoxy system, the ultra-thin sections were stained for 5 min in a tetra-hydrofuran solution containing 1 w/v% osmium tetraoxide (Os[O.
They were then post-fixed with 1% osmium tetraoxide and dehydrated in an increasing gradient of ethanol solutions.
The samples were post-fixed with 1% osmium tetraoxide in the sodium phosphate buffer, were rinsed with distilled water and dehydrated in a ethanol gradient.