Orthopoxvirus

(redirected from Orthopoxvirus infections)

orthopoxvirus

 [or´tho-poks-vi″rus]
any member of a genus of poxviruses, including the viruses that cause human smallpox and vaccinia.

Or·tho·pox·vi·rus

(ōr'thō-poks'vī-rŭs),
The genus of the family Poxviridae, which comprises the viruses of alastrim, vaccinia, variola, cowpox, ectromelia, monkeypox, and rabbitpox.

Orthopoxvirus

/Or·tho·pox·vi·rus/ (or´tho-poks-vi″rus) a genus of viruses of the subfamily Chordopoxvirinae (family Poxviridae) that cause generalized infections with a rash in mammals, including cowpox, monkeypox, and variola viruses.

orthopoxvirus

[or′thopoksvi′rus]
any member of a genus of poxviruses, including the viruses that cause human smallpox and vaccinia.

Or·tho·pox·vi·rus

(ōr'thō-poks'vī'rŭs)
The genus of the family Poxviridae that comprises the Alastrim, Vaccinia, Variola, Cowpox, Ectromelia, Monkeypox, and Rabbitpox viruses.

Orthopoxvirus

The genus of viruses that includes monkeypox, smallpox, cowpox, and camelpox.
Mentioned in: Monkeypox

Orthopoxvirus

a genus in the family Poxviridae.

O. infections
see pox.
References in periodicals archive ?
His research interest is the genomic study of filovirus and orthopoxvirus infections.
PCR is a relatively simple, rapid, and accurate method for detection and differential diagnosis of several different orthopoxvirus infections.
In addition, with further development it holds promise for treatment of other human orthopoxvirus infections.
7 Million challenge grant from the National Institutes of Health (NIH) to support the development of protease inhibitors to treat orthopoxvirus infections, such as smallpox and monkeypox.
However, several suspected monkeypox cases we investigated were later found to have alternative, laboratory-confirmed diagnoses, thus making anecdotal accounts of possible past human monkeypox outbreaks impossible to confirm as orthopoxvirus infections.
This is the first time we have data in primates that confirm a drug's potential activity against orthopoxvirus infections," Dr.
Serologic cross-reactivity between orthopoxviruses is a substantial barrier to laboratory diagnosis of specific orthopoxvirus infections and epidemiologic characterization of disease outbreaks.
It also highlights the need for increased awareness regarding clinical features of orthopoxvirus infections and the importance of developing new antiviral drugs against orthopoxviruses.
A proposed new small-animal (rodent) model for studying the pathogenesis and treatment of severe orthopoxvirus infections is described.
The pathologic findings in this study of prairie dogs can be used to better define possible transmission routes and pathogenesis of human and animal monkeypox, and such a model may help develop new vaccine and treatment strategies for orthopoxvirus infections.
The team has continued investigating whether human chemokine receptors are involved as host factors in orthopoxvirus infections.
Of 72 retrospectively identified cases tested, 54% had antibodies by plaque-reduction assay, a preferred test for verifying orthopoxvirus infections during smallpox eradication (20,21).