Orthomyxoviridae

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Or·tho·myx·o·vir·i·dae

(ōr'thō-mik'sō-vir'i-dē),
The family of viruses that contains the three genera of influenza viruses, types A and B, C, and Thogoto-like viruses. Virions are roughly spheric or filamentous, and the former (the more common form) are 80-120 mm in diameter and ether-sensitive; envelopes are studded with surface projections; nucleocapsids are of helical symmetry, 6-9 nm in diameter, and contain single-stranded, segmented RNA. The nucleoprotein antigen of each type of virus is common to all strains of the type but is distinct from those of the other types; the mosaic of surface antigens varies from strain to strain. Nucleocapsids seem to be formed in the nuclei of infected cells, hemagglutinin, and neuraminidase in the cytoplasm; virus maturation occurs during budding of the cell membrane. Influenza virus types A and B are subject to mutation resulting in epidemics. Influenza virus C differs from types A and B (for example, lacks neuraminidase) and belongs to a separate genus.
See also: Influenza virus.

Or·tho·myx·o·vir·i·dae

(ōr'thō-mik'sō-vir'i-dē)
The family of viruses that comprises the three groups of influenza viruses, types A, B, and C. The only recognized genus is Influenzavirus, which comprises the strains of virus types A and B, both of which are subject to mutation resulting in epidemics. Influenza virus type C differs from types A and B somewhat and probably belongs to a separate genus.
See also: Influenzavirus

Or·tho·myx·o·vir·i·dae

(ōr'thō-mik'sō-vir'i-dē)
The family of viruses that comprises the three groups of influenza viruses, types A, B, and C. The only recognized genus is Influenzavirus (q.v.), which comprises the strains of virus types A and B, both of which are subject to mutation resulting in epidemics.

Orthomyxoviridae

a family of viruses containing influenza viruses A, B and C of which only influenza A viruses cause disease in domestic animals. Virions are 100 nm diameter, enveloped and contain a single-stranded negative sense RNA genome in eight segments. The envelope carries two glycoprotein spikes, hemagglutination (H) and neuraminidase (N), each of which is coded for by a different genome segment and undergo continuous antigenic variation, either because of mutation (antigenic drift) or genetic recombination (antigenic shift).
References in periodicals archive ?
A review of the Orthomyxoviridae Infections products under development by companies and universities/research institutes based on information derived from company and industry-specific sources.
Coverage of the Orthomyxoviridae Infections pipeline on the basis of route of administration and molecule type.
Identify and understand important and diverse types of therapeutics under development for Orthomyxoviridae Infections.