Orthomyxoviridae


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

Or·tho·myx·o·vir·i·dae

(ōr'thō-mik'sō-vir'i-dē),
The family of viruses that contains the three genera of influenza viruses, types A and B, C, and Thogoto-like viruses. Virions are roughly spheric or filamentous, and the former (the more common form) are 80-120 mm in diameter and ether-sensitive; envelopes are studded with surface projections; nucleocapsids are of helical symmetry, 6-9 nm in diameter, and contain single-stranded, segmented RNA. The nucleoprotein antigen of each type of virus is common to all strains of the type but is distinct from those of the other types; the mosaic of surface antigens varies from strain to strain. Nucleocapsids seem to be formed in the nuclei of infected cells, hemagglutinin, and neuraminidase in the cytoplasm; virus maturation occurs during budding of the cell membrane. Influenza virus types A and B are subject to mutation resulting in epidemics. Influenza virus C differs from types A and B (for example, lacks neuraminidase) and belongs to a separate genus.
See also: Influenza virus.

Or·tho·myx·o·vir·i·dae

(ōr'thō-mik'sō-vir'i-dē)
The family of viruses that comprises the three groups of influenza viruses, types A, B, and C. The only recognized genus is Influenzavirus, which comprises the strains of virus types A and B, both of which are subject to mutation resulting in epidemics. Influenza virus type C differs from types A and B somewhat and probably belongs to a separate genus.
See also: Influenzavirus

Or·tho·myx·o·vir·i·dae

(ōr'thō-mik'sō-vir'i-dē)
The family of viruses that comprises the three groups of influenza viruses, types A, B, and C. The only recognized genus is Influenzavirus (q.v.), which comprises the strains of virus types A and B, both of which are subject to mutation resulting in epidemics.

Orthomyxoviridae

a family of viruses containing influenza viruses A, B and C of which only influenza A viruses cause disease in domestic animals. Virions are 100 nm diameter, enveloped and contain a single-stranded negative sense RNA genome in eight segments. The envelope carries two glycoprotein spikes, hemagglutination (H) and neuraminidase (N), each of which is coded for by a different genome segment and undergo continuous antigenic variation, either because of mutation (antigenic drift) or genetic recombination (antigenic shift).
References in periodicals archive ?
Taken together these data clearly demonstrate a very strong antiviral activity of Bioaron C[R] against all members of the orthomyxoviridae family tested.
A snapshot of the global therapeutic scenario for Orthomyxoviridae Infections.
Quaranfil, Johnston Atoll, and Lake Chad viruses are novel members of the family Orthomyxoviridae.
Influenza is caused by influenza virus, a member of the Orthomyxoviridae family and there are three serotypes of influenza virus (A, B, and C) (Figure 7-21).
One RNA virus of concern is the Avian influenza virus, from the family Orthomyxoviridae, which has caused historic pandemics (strains H3N2 and H1N1) and is the virus most likely to cause the next global pandemic, specifically the highly pathogenic H5N1.
It also reviews key players involved in the therapeutic development for Orthomyxoviridae Infections.
Electron microscopy of virus particles demonstrated filamentous and spherical particles consistent with the morphology of the family Orthomyxoviridae.
La influenza aviar es una enfermedad viral altamente contagiosa causada por un virus ARN de la familia Orthomyxoviridae tipo A (unico capaz de provocar infecciones en aves).
The genus Influenza virus is part of the family Orthomyxoviridae, which are single-stranded, enveloped RNA viruses that undergo frequent mutations.
Genetic analysis of the putative PBl protein of TiLVs from Thailand and the viruses of the family Orthomyxoviridae showed that TiLVs from Thailand possessed motifs preA, A, B, C, D, and E similar to those of Orthomyxoviridae viruses, including influenza A, B, and C viruses; infectious salmon anemia virus; Dhori virus; and Thogoto virus (online Technical Appendix Table 4) (8-10).
Avian influenza viruses (AIV) are placed in the family of Orthomyxoviridae having three influenza genera known as A, B and C.