Orthomyxoviridae


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Or·tho·myx·o·vir·i·dae

(ōr'thō-mik'sō-vir'i-dē),
The family of viruses that contains the three genera of influenza viruses, types A and B, C, and Thogoto-like viruses. Virions are roughly spheric or filamentous, and the former (the more common form) are 80-120 mm in diameter and ether-sensitive; envelopes are studded with surface projections; nucleocapsids are of helical symmetry, 6-9 nm in diameter, and contain single-stranded, segmented RNA. The nucleoprotein antigen of each type of virus is common to all strains of the type but is distinct from those of the other types; the mosaic of surface antigens varies from strain to strain. Nucleocapsids seem to be formed in the nuclei of infected cells, hemagglutinin, and neuraminidase in the cytoplasm; virus maturation occurs during budding of the cell membrane. Influenza virus types A and B are subject to mutation resulting in epidemics. Influenza virus C differs from types A and B (for example, lacks neuraminidase) and belongs to a separate genus.
See also: Influenza virus.

Or·tho·myx·o·vir·i·dae

(ōr'thō-mik'sō-vir'i-dē)
The family of viruses that comprises the three groups of influenza viruses, types A, B, and C. The only recognized genus is Influenzavirus, which comprises the strains of virus types A and B, both of which are subject to mutation resulting in epidemics. Influenza virus type C differs from types A and B somewhat and probably belongs to a separate genus.
See also: Influenzavirus

Or·tho·myx·o·vir·i·dae

(ōr'thō-mik'sō-vir'i-dē)
The family of viruses that comprises the three groups of influenza viruses, types A, B, and C. The only recognized genus is Influenzavirus (q.v.), which comprises the strains of virus types A and B, both of which are subject to mutation resulting in epidemics.

Orthomyxoviridae

a family of viruses containing influenza viruses A, B and C of which only influenza A viruses cause disease in domestic animals. Virions are 100 nm diameter, enveloped and contain a single-stranded negative sense RNA genome in eight segments. The envelope carries two glycoprotein spikes, hemagglutination (H) and neuraminidase (N), each of which is coded for by a different genome segment and undergo continuous antigenic variation, either because of mutation (antigenic drift) or genetic recombination (antigenic shift).
References in periodicals archive ?
Taken together these data clearly demonstrate a very strong antiviral activity of Bioaron C[R] against all members of the orthomyxoviridae family tested.
Coverage of the Orthomyxoviridae Infections pipeline on the basis of route of administration and molecule type.
Quaranfil, Johonston Atoll, and Lake Chad viruses are novel members of the family Orthomyxoviridae.
This study shows that the morphologic features of pandemic (H1N1) 2009 virus in infected cells were similar to other members of the family Orthomyxoviridae (7).
Influenza viruses are segmented, negative-sense RNA viruses belonging to the family Orthomyxoviridae.
Avian influenza virus A refers collectively to a group of viruses within the family Orthomyxoviridae that has a worldwide distribution and causes a variety of diseases in birds.
Influenza viruses are segmented, negative-strand RNA viruses that are placed in the family Orthomyxoviridae in 3 genera: Influenzavirus A, B, and C.
Previous surveillance reports based on virus isolations or serologic studies in cattle from Kenya, the Central African Republic, and South Africa have identified tickborne arboviruses from the Bunyaviridae, Flaviviridae, Rhabdoviridae, Reoviridae, and Orthomyxoviridae (1-4).
Influenza is a negative-strand RNA virus that belongs to the family Orthomyxoviridae, which consists of 4 genera: influenza A, influenza B, influenza C, and Thogoto viruses.
Influenza viruses are segmented negative-sense, single-stranded RNA viruses of the family Orthomyxoviridae and are divided into the genera Influenzavirus A, B and C.