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ornithine
(redirected from Ornithine transcarbamylase)

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
ornithine /or·ni·thine/ (or´nĭ-thēn) an amino acid obtained from arginine by splitting of urea; it is an intermediate in urea biosynthesis.
or·ni·thine (ôrn-thn)
n.
Abbr. Orn An amino acid formed by the hydrolysis of arginine and important in the formation of urea.

ornithine
[ôr′nithēn]
an amino acid, not a constituent of proteins, that is produced as an important intermediate substance in the urea cycle. It is formed by the hydrolization of arginine by arginase and is subsequently converted into citrulline. It decomposes by losing carbon dioxide, producing putrescine and a strong foul odor characteristic of decaying animal tissue. Also called diaminovaleric acid.

ornithine [or´nĭ-thēn]
an amino acid obtained from arginine by splitting of urea; it is an intermediate in urea biosynthesis.
ornithine carbamoyltransferase (ornithine transcarbamylase) an enzyme that catalyzes a reaction occurring in the liver mitochondria as part of the urea cycle.

ornithine (ôr´nthēn´),
n an amino acid, not a constituent of proteins, that is produced as an important intermediate substance in the urea cycle.
ornithine carbamoyltransferase,
n an enzyme in the blood that increases in patients with liver and other diseases.

ornithine
an amino acid obtained from arginine by the action of the enzyme arginase which also splits off urea; it is an intermediate in urea biosynthesis.

ornithine carbamoyl transferase (OCT), ornithine transcarbamoylase
see ornithine carbamoyl transferase.
ornithine cycle
alternative name for urea cycle since ornithine is the carrier of the nitrogens.
ornithine decarboxylase test
a means of identifying different members of the Enterobacteriaceae as well as other gram-negative bacteria.
ornithine-δaminotransferase
deficiency see gyrate atrophy.


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An 18-year-old named Jesse Gelsinger suffered from a genetic disorder, partial ornithine transcarbamylase (OTC) deficiency, that put him in constant danger of building up toxic amounts of ammonia in his blood.
He was suffering from a potentially fatal disease known as ornithine transcarbamylase deficiency (OTD), which prevents the liver from breaking down protein.
Ethical concerns regarding gene therapy trials peaked in 1999, when Jesse Gelsinger, an 18-year-old patient with ornithine transcarbamylase deficiency, died shortly after undergoing an investigational gene transfer procedure using an adenoviral vector.
 
 
ornithine
ornithine
ornithine alpha-ketoglutarate
ornithine alpha-ketoglutarate
Ornithine aminotransferase
ornithine carbamoyl transferase (OCT)
ornithine carbamoyl transferase (OCT)
ornithine carbamoyl transferase (OCT)
ornithine carbamoyl transferase (OCT), ornithine transcarbamoylase
ornithine carbamoyl transferase (OCT), ornithine transcarbamoylase
ornithine carbamoyl transferase (OCT), ornithine transcarbamoylase
Ornithine carbamoyltransferase
Ornithine carbamoyltransferase
Ornithine carbamoyltransferase
Ornithine carbamoyltransferase
ornithine carbamoyltransferase deficiency
ornithine carbamoyltransferase deficiency
ornithine carbamoyltransferase deficiency
Ornithine carbamoyltransferase deficiency disease
Ornithine cycle
Ornithine cycle
Ornithine cycle
Ornithine cycle
Ornithine cycle
Ornithine decarboxylase
ornithine decarboxylase test
ornithine decarboxylase test
ornithine decarboxylase test
Ornithine transcarbamoylase
Ornithine transcarbamoylase deficiency
Ornithine transcarbamylase
Ornithine transcarbamylase deficiency
Ornithine transcarbamylase deficiency
Ornithine translocase deficiency
Ornithine Vasotocin
ornithine-deltaaminotransferase
ornithine-deltaaminotransferase
ornithine-deltaaminotransferase
Ornithine-urea cycle
Ornithine-urea cycle
ornithinemia
ornithinemia, type I
ornithinemia, type II
ornithinuria
Ornithischia
Ornithischia
ornithischian
ornithischian
ornithischian dinosaur
Ornithischians
Ornithischians
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Ornithobacterium rhinotracheale
Ornithobilharzia
Ornithobilharzia bomfordi
Ornithobilharzia turkestanicum
Ornithobius mathisi
Ornithochory
Ornithocoris
Ornithodelphia
Ornithodelphia
 
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