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transplant rejection
(redirected from Organ rejection)

   Also found in: Wikipedia 0.01 sec.
transplant
1. an organ or tissue taken from the body and grafted into another area of the same individual or another individual.
2. to transfer tissue from one part to another or from one individual to another.

ovum transplant
see ovum transplant.
transplant rejection

transplant rejection
Graft rejection, organ rejection, tissue rejection Immunology The constellation of host immune responses evoked when an allograft tissue is transplanted into a recipient; rejection phenomena may be minimized by optimal matching of MHC antigens and ABO blood groups and ameliorated with immunosuppressants–eg, cyclosporin, tacrolimus, rapamycin Exceptions of TR Corneal transplants, identical twins. See Graft-versus-host disease, HLA, MHC, Tissue typing.


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Biomarkers in Transplantation, a research initiative that will allow doctors to identify patients rejecting transplanted organs with a simple blood test, is making use of advanced genomic, proteomic, and computational tools to develop the test, which will diagnose rejection before acute organ rejection occurs, allowing doctors to intervene early and to personalize a patient's immunosuppressant therapy.
Chemists in Taiwan are reporting that an ingredient in licorice widely used in various foods and herbal medicines appears to block the absorption of cyclosporine, a drug used by transplant patients to prevent organ rejection.
Previous studies had found that B-cells play a large role in organ rejection by making immune proteins that attack transplants.
 
 
 
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