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opioid antagonist

   Also found in: Wikipedia 0.01 sec.
opioid antagonist,
a drug that blocks mu, kappa, or delta opioid receptors, used primarily in the treatment of opioid-induced mu receptor-mediated respiratory depression. The opioid antagonist naloxone is administered parenterally, wheras naltrexone is administered orally.


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The opioid antagonist naltrexone significantly reduced stealing urges and behaviors associated with kleptomania, compared with placebo in a small, randomized, double-blind study.
Naltrexone promising for treating urges and behavior in kleptomania by McNamara, Damian / Clinical Psychiatry News
An opening description of the history behind the clinical development of the classic opioid antagonist naltrexone is followed by sections on opioid receptors; the chemistry and pharmacology of opioid antagonists; the therapeutic areas of opioid antagonists for substance abuse, alcohol and ingestive behaviors, behavioral disorders, and medical indications, supported by nonclinical and clinical evidence; and the development of exciting and innovative drug-delivery approaches.
Opiate receptors and antagonists; from bench to clinic by SciTech Book News
About EMBEDA[TM] Utilizing King's proprietary technology, EMBEDA[TM]Capsules contain extended-release morphine pellets, each with a sequestered core of naltrexone, an opioid antagonist.
King Pharmaceuticals Provides Update on EMBEDA[TM] NDA Review by Business Wire
 
 
 
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