open-label study


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Related to open-label study: Prospective study, Double blind study

open-label study

a study in which there is no blinding of treatments.

open-label study

A clinical study in which the patients/subjects and investigators know which product each patient/subject is receiving, which is the opposite of a blinded study.

open-label study

, open label study
A clinical trial without a control group, in which both patients and researchers know the identity of the treatment and its dosage.
See also: study
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In a 12-week open-label study of 102 patients diagnosed with bipolar I disorder in a manic or mixed phase, risperidone at a mean dosage of 2 mg/day was added to one or two mood stabilizers: lithium (0.
In addition to the open-label study, NexMed is also conducting two multi-center, double-blind, placebo-controlled, randomized Phase 3 studies which were initiated in November 2001.
We are pleased that the open-label study results further support the safety profile of ATX-101 for the reduction of submental fat and are consistent with our previous Phase II and the European Phase III trials," said Patricia S.
This multicenter, open-label study enrolled patients with a current or previous diagnosis of LGS aged 2 to 60 years old.
In the open-label study, most of the children continued to respond favorably to risperidone.
9% of patients completing the 12-week treatment period of the open-label study
The open-label study is being planned under a different protocol that will be submitted to the FDA.
Of 246 patients in an Eli Lilly-funded, open-label study, 79% responded to 12 weeks of treatment with a single weekly dose of 90 mg of enteric-coated fluoxetine, following 6 to 52 weeks of successful treatment with citalopram (83), paroxetine (77), or sertraline (86).
The use of hypericum extract L1160 in an open-label study of 12 patients with depression led to significant decreases in steady-state amitriptyline and all of its metabolites (except for the E-10 hydroxylated metabolite of nortriptyline) from O to 12 hours after dosing.
The multi-center, open-label study will evaluate up to 42 patients treated with DAVANAT([R]) and 5-FU for at least two cycles or to disease progression.