octreotide


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octreotide

 [ok-tre´o-tīd]
a synthetic analogue of somatostatin, used as the acetate ester in palliative treatment of symptoms of gastrointestinal endocrine tumors and in treatment of acromegaly; administered subcutaneously, intragluteally, or intravenously.

oc·tre·o·tide

(ok'trē-ō-tīd),
Somatostatin analogue used to treat secretory diarrheal states and gastrointestinal bleeding.

octreotide

/oc·tre·o·tide/ (ok-tre´o-tīd) a synthetic analogue of somatostatin, used as the acetate ester in the palliative treatment of the symptoms of gastrointestinal endocrine tumors and in the treatment of acromegaly.

octreotide

an antidiarrheal and hormone.
indications The two brand names of this drug are used for different purposes. Sandostatin is used to treat acromegaly, carcinoid tumors, and vasoactive intestinal peptide tumors (VIPomas). Sandostatin LAR Depot is used for long-term maintenance of acromegaly, carcinoid tumors, and VIPomas.
contraindications Known hypersensitivity to this drug prohibits its use.
adverse effects Life-threatening effects include seizure, arrhythmias, congestive heart failure, hepatitis, GI bleeding, and pancreatitis. Other adverse effects are depression, anxiety, tremors, paranoia, chest pain, shortness of breath, thrombophlebitis, ischemia, hypertension, palpitations, galactorrhea, diabetes insipidus, increased liver function tests, urinary tract infection, pollakiuria, hematoma and inflammation of the injection site, bruising, rash, urticaria, and pain. Common side effects include headache, dizziness, fatigue, weakness, sinus bradycardia, conduction abnormalities, hyperglycemia, ketosis, hypothyroidism, hypoglycemia, diarrhea, nausea, abdominal pain, vomiting, flatulence, distension, constipation, and joint and muscle pain.

octreotide

An hormone inhibitor analogue of the natural substance SOMATOSTATIN. Octreotide has a much longer effective time of action than somatostatin and is selective in its action on secretion of growth hormone, GASTRIN, SECRETIN and MOTILIN. It is also effective against various tumours of the ENDOCRINE system. A brand name is Sandostatin.

octreotide

a somatostatin analog used in the treatment of endocrine disorders of the pituitary and pancreas.
References in periodicals archive ?
contract awarded for:quotation for the supply of octreotide 10mg vials
s investigational new drug, octreotide acetate for intranasal administration, for the treatment of acromegaly, the company said.
According to the company, DP1038 is its investigational new drug octreotide acetate for intranasal administration.
The approval was based on a Phase 3 study which demonstrated a 79% reduction in the risk of disease progression or death within the Lutathera plus best standard of care arm compared to 60 mg of octreotide LAR alone.
This study aimed to evaluate short-term preoperative octreotide (OCT) use in TSHoma patients and to investigate SSTR2 and SSTR5 expression and observe structural changes in tumor tissue.
Octreotide acetate is a somatostatin analogue established in the treatment of chylothorax; however, its utility in the management of cervical chylous fistulae has not been fully evaluated.
Test the therapeutic efficacy of Sapylin in resolving persistent Congenital Chylothorax (CC) in four infants who failed to respond to conservative medical therapy including Erythromycin and/or Octreotide management.
Fox is currently undergoing Octreotide treatment for the tumors with monthly injections.
With a strong pathophysiological basis, yet conflicting results with somatostatin and its analogue in the management of acute pancreatitis, we set forth with the current study to see the effect of octreotide in acute pancreatitis patients of Kolkata, India.
En los pacientes que tienen sintomas de sindrome carcinoide, los analogos de somatostatina, como octreotide, son sumamente eficaces para controlar los sintomas.
Bromocriptine, cabergoline and octreotide or different combinations of these drugs are used in treatment and pegvisomant has also been used in recent years.
111]In octreotide scintigraphy showed increased uptake of the nodule (Figure 1B, arrow).