TCF7L2

(redirected from OTTHUMP00000020496)

TCF7L2

A gene on chromosome 10q25.3 that encodes a high mobility group (HMG)-box-containing transcription factor, which plays a key role in Wnt-signalling pathway, glucose homeostasis and key developmental and growth regulatory mechanisms of cells.

Molecular pathology
TCF7L2 mutation increases the risk of type-2 diabetes.