OCRL


Also found in: Acronyms, Wikipedia.

OCRL

A gene on chromosome Xq25 that encodes phosphatidylinositol polyphosphate 5-phosphatase, an enzyme involved in actin polymerisation and possibly also in lysosomal membrane trafficking.

Molecular pathology
OCRL mutations cause oculocerebrorenal syndrome of Lowe and Dent disease.
References in periodicals archive ?
Addis M, Meloni C, Tosetto E, Ceol M, Cristofaro R, Melis MA, Vercelloni P, Del Prete D, Marra G, Anglani F, An atypical Dent's disease phenotype caused by co-inheritance of mutations at CLCN5 and OCRL genes.
Throughout the process, the OCRL fostered a bipartisan approach to resolving the issue.
In response, the OCRL intends to develop a grassroots campaign--relying on the opinion leaders, including churches and the editorial boards of major Ohio newspapers, who helped bring about this June's reform victory.