MC3R

(redirected from OB20)

MC3R

A gene on chromosome 20q13.2-q13.3 that encodes a receptor for alpha, beta and gamma melanocyte stimulating hormone (MSH), the activity of which is mediated by G protein-activated adenylate cyclase. MC3R is expressed in tissues other than the adrenal cortex and melanocytes.

Molecular pathology
MC3R mutations are associated with susceptibility to obesity.
References in periodicals archive ?
In addition, 10 RAPD primers, created 127 polymorphic among them OPA-01with 22 bands and BB13 and OC4 primers with 19 and 18 bands had the highest number of polymorphic bands and OS-03 and OB20 with 14 and 15 bands had the lowest number of polymorphic bands respectively.
58 RAPD OB20 5' GGACCCTTAC 3' 9 15 OH-04 5' GGAAGTCGCC 3' 11 17 OA12 5' TCGGCGATAG 3' 14 18 BB13 5' TTCCCCCGCT 3' 17 20 SA-R 5' AGGTCACTGA 3' 10 16 CS-56 5' TGGTGGGTCC 3' 12 16 OC4 5' CCGCATCTAC 3' 15 19 OS-03 5' CAGAGGTCCC 3' 9 14 OPA-01 5' CAGGCCCTTC 3' 17 22 OPC-04 5' CCGCATCTAC 3' 13 18 Average 12.