SLCO1C1

(redirected from OATP-F)

SLCO1C1

A gene on chromosome 12p12.2 that encodes a protein which mediates Na+-independent high-affinity transport of organic anions (e.g., thyroxine and rT3) and lower-affinity transport of other substrates (e.g., triiodothyronine, 17-beta-glucuronosyl oestradiol, oestrone-3-sulfate and sulfobromophthalein). SLCO1C1 is thought to play a major role in regulating T4 flux in the brain.
References in periodicals archive ?
Polyclonal goat antibodies against OATP-D (mOatp3al), OATP-3 (mOatpla5), OATP-E (mOatp4al), OATP-F (mOatplcl), OATP-B (mOatp2bl) (1:100; all from Santa Cruz Biotechnology, Santa Cruz, CA, USA), and mOatplb2 (1:1,000; kindly provided by CD.