number needed to treat

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number needed to treat

In a clinical treatment regimen, the numeric cohort of patients who must be treated to prevent the occurrence of specified complications or adverse outcomes of the condition under examination.

number needed to treat

Decision-making The minimum number of Pts to whom a particular intervention must be administered in a trial or controlled study to prevent a single target event. See Absolute risk reduction, Odds ratio, Relative risk reduction, Threshold NNT.

number needed to treat

The number of patients who must receive a specific therapy (or undergo a specific medical test) so that one of them will benefit. This concept is important in assessing the relative values and costs of interventions for specific illnesses. For example, to prevent one death from breast cancer, the number of patients who need annual mammography can be calculated. Similarly, the number of patients with cancer who will survive because of the use of a particular chemotherapy can be assessed. Generally, the smaller the number needed to treat, the greater the value of the intervention. This comparative information can be used to decide how to allocate resources, plan studies, or make recommendations to patients about their care.
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Hence, with the numbers needed to treat presented by Xie and colleagues (94 for high-risk patients and 186 for all other included patients), this finding will be of great interest from the point of view of public health, and probably beneficial from a health economic perspective.
Results from an indirect analysis of the numbers needed to treat (NNT) for lenvatinib and sorafenib in the SELECT and DECISION trials respectively will also be presented at ITC 2015.
By comparison, he said, the numbers needed to treat with simvastatin or ramipril for 5 years were 30 and 59, respectively.
Therefore, the numbers needed to treat to save one life ranged from 11-20 patients.
BP and lipid control are the 'low hanging fruit' of CV protection - they are often easier to achieve than tight glycaemic control and the numbers needed to treat (NNT) are lower.
In terms of numbers needed to treat (NNT), BALANCE showed that seven bipolar patients would need to receive combination therapy for 2 years instead of valproate in order for there to be one fewer relapse; that's a very favorable NNT, Dr.
Further research is needed to confirm these findings and to identify the numbers needed to treat to prevent one case from progressing from early to late AMD.
STATA 10 (CollegeStation, Texas, USA) was used to calculate the risk ratio for the primary outcomes, absolute risk reduction and the numbers needed to treat.
Finally, the numbers needed to treat (NNT) and numbers needed to harm (NNH) statistics (Altman 1998) were calculated.
Numbers needed to treat for harm range from 2 to 30.
To provide perspective, the following discussion focuses on the absolute risk reduction and the numbers needed to treat associated with two preventive health measures that have been widely researched and endorsed: (1) preventing coronary artery disease by treating hypercholesterolemia and (2) preventing fractures by treating osteoporosis.
BP and lipid control are the 'low hanging fruit' of CV protection--they are often easier to achieve than tight glycaemic control and the numbers needed to treat (NNT) are lower.